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Endometriosis 2026: A Nerve-Centric Disease is the first meeting in the field to place the nervous system at the center of endometriosis biology and surgical care. Held in Times Square, New York City, this two-day international conference brings together more than 35 leading experts to bridge advanced neuroscience with advanced endometriosis surgery.
The program reframes endometriosis as a neuroinflammatory, nerve-driven disease extending beyond the pelvis, exploring neuro-immune signaling, neuroangiogenesis, perineural fibrosis, and organ-specific pain across pelvic and extra-pelvic disease, including thoracic and sciatic endometriosis. Through integrated Science and Surgery sessions, the meeting spans discovery to practice—advancing understanding from molecular and neural circuits to real-world diagnosis, treatment, surgical management, pain control, and multidisciplinary care for clinicians, researchers, patients, caregivers, and advocates.
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| Time | Topic | Speaker | Moderators |
| 07:30 am - 08:00 am | Registration | ||
| 08:00 am - 08:10 am | Welcome: The Big Nerve and Endometriosis | Tamer Seckin, MD Dan Martin, MD Frank Chervenak, MD |
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| Session I: | |||
| 08:10 am - 08:30 am | Recognition of Endometriosis | Dan Martin, MD | |
| 08:30 am - 08:50 am | Cancer-driver Mutation and Nerve Innervation in Endometriosis | Ie- Ming Shih, | |
| 08:50 am - 09:10 am | TBD (V) | Philippe Koninckx, MD | |
| 09:10 am - 09:30 am | Neurogenic inflammation in peritoneal lesions and clinical consequences | Sylvia Mechsner, MD | |
| 09:30 am - 09:45 am | Discussion | ||
| 09:45 am - 10:00 am | Break | ||
| Session II: | |||
| 10:00 am - 10:20 am | Neuromodulation of neuro-immune circuits | Stavros Zanos, MD, PhD | |
| 10:20 am - 10:40 am | Spleen neuro-immune interactions and inflammation | Ibrahim T. Mughrabi, MD, PhD | |
| 10:40 am - 11:00 am | Neuroimmune communication drives lesions and pain in endometriosis | Michael S. Rogers PhD | |
| 11:00 am - 11:20 am | Central sensitization driven by neuroinflammation in endometriosis | Kanako Hayashi, PhD. | |
| 11:20 am - 11:40 am | Preclinical Modeling of Endometriosis-Associated Pain: Neural Remodeling and Disease Pathophysiology | Jae-Wook Jeong, PhD | |
| 11:40 am - 11:55 am | Discussion | ||
| 11:55 am - 12:10 pm | Break | ||
| 12:10 pm 12:45 pm |
Keynote: Vagus Nerves in Endometriosis: Role and Therapeutic Potentials | Sun-Wei Guo, PhD | |
| 12:45 pm - 13:30 pm | Lunch | ||
| Session III | |||
| 13:30 pm - 13:50 pm | From Menstrual Effluent to Nociceptors: Neutrophils Triggering Endometriosis Pain | Katherine Burns, PhD | |
| 01:05 pm - 01:25 pm | TBD | - | |
| 02:10 pm - 02:30 pm | Nociception in Endometriosis Lesions: Insights from High Resolution Molecular Mapping and Neuro-Immune networks | Elise Courtois, PhD. | |
| 02:40 pm - 03:00 pm | Multi-omic Analysis of Human Endometrium and Endometriosis | Semir Beyaz, PhD | |
| 03:00 pm - 03:15 pm | Discussion | ||
| 03:15 pm - 03:30 pm | Break | ||
| Session IV: | |||
| 11:20 am - 11:40 am | Adenomyosis and Pain: The Hidden Drivers of Uterine Pain—From Myometrium to Nociceptors | Sun-Wei Guo, PhD | |
| 03:50 pm - 04:10 pm | TBD | - | |
| 04:10 pm - 04:30 pm | TBD | - | |
| 04:30 pm - 04:50 pm | TBD | - | |
| 04:50 pm - 05:00 pm | Discussion | ||
| 05:00 pm - 05:30 pm | End of the Day | Tamer Seckin, MD Dan Martin, MD |
|
| 07:00 pm - 10:00 pm | FACULTY DINNER | ||
*The scheduled timing of speakers on the program is subject to change.
| Time | Topic | Speaker | Moderators |
| 07:30 am - 07:50 am | Welcome Day 2 Surgery: Endometriosis 2026: The Big Nerve and Endometriosis | Tamer Seckin, MD Harry Reich, MD |
|
| 07:50 am - 08:10 am | TBD | Harry Reich, MD | |
| Session I | |||
| 08:10 am - 08:30 am | The hypothalamus: control of the circle of pain in endometriosis | Serdar Bulun, MD | |
| 08:30 am - 08:50 am | Depression in endometriosis | Hugh Taylor, MD | |
| 08:50 am - 09:10 am | Endometrial Panic: A Psychobiological Phenomenon | Arnold Wilson, PhD | |
| 09:10 am - 09:30 am | Functional brain MRI under different medications in endometriosis patients | Wolfgang Küpker, MD, PhD | |
| 09:30 am - 09:50 am | Imaging Diagnosis for Endometriosis Involving Nerves | Mauricio Abrao, MD | |
| 09:50 am - 10:10 am | Discussion | ||
| 10:10 am - 10:30 am | Break | ||
| Session II | |||
| 10:30 am - 10:50 am | Beyond Endometriosis: Why Neuropelveological Expertise Is Essential to Understand Pelvic Pain (V) | Marc Possover, MD | |
| 10:50 am - 11:10 am | Why is Endometriosis is a Neurocentric Disease | Tamer Seckin, MD | |
| 11:10 am - 11:30 am | Nerve-Centric Surgical Planning in Endometriosis: From Neuroinflammation to Excision Strategy | Hélder Ferreira MD, PhD, MBA | |
| 11:30 am - 11:50 am | Dealing with endometriosis of pelvic nerves: My way (V) | Horace Roman, MD | |
| 11:50 am - 12:05 pm | Discussion | ||
| 12:05 pm - 12:15 pm | Break | ||
| 12:15 pm 01:00 pm |
Keynote: | Assia Stepanian, MD | |
| 01:00 pm - 01:45 pm | Lunch | ||
| Session III | |||
| 01:45 pm - 02:05 pm | The Endometriosis Pain Paradox: Why Suppressing Estrogen Isn’t Enough | Michael Nimaroff, MD, MBA | |
| 02:05 pm - 02:25 pm | Presentation of 4 case reports with lumbosacral endometriosis and treatment strategies | Sylvia Mechsner, MD | |
| 02:25 pm - 02:45 pm | Presacral Neurectomy in a Nerve‑Centric Era: Selective Denervation for the Right Patient | Ted Lee, MD | |
| 02:45 pm - 03:05 pm | Mind the Nerves: Impact of Deep Endometriosis Surgery on Bladder Function | Fatih Sendag, MD | |
| 03:05 pm - 03:25 pm | Laparoscopic Pudendal Nerve Decompression for Pudendal Neuralgia Refractory to Conservative Management | Liron Bar-el, MD | |
| 03:25 pm - 03:40 pm | Discussion | ||
| 03:40 pm - 03:55 pm | Break | ||
| Session IV | |||
| 03:55 pm - 04:15 pm | Pregnancy in Endometriosis and Adenomyosis: Maternal–Fetal Risks | Anthony Vintzileos, MD | |
| 04:15 pm - 04:35 pm | Egg freezing Or Endometriosis surgery - what should come first ?! | Tomer Singer, MD, MBA | |
| 04:35 pm - 04:55 pm | Modern Advancements in IVF Treatments | Brian Levine, MD | |
| 04:55 pm - 05:15 pm | TBD | Serin Seckin, MD | |
| 05:15 pm - 05:30 pm | Closing Remarks | ||
*The scheduled timing of speakers on the program is subject to change.
